Lactoferrin anticorps

N° du produit ABIN1107996

Cet anticorps anti-Lactoferrin est un anticorps Souris Monoclonal détectant Lactoferrin dans WB et EIA. Adapté pour Boeuf (Vache). Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour Lactoferrin anticorps (ABIN1107996)

Antigène: Lactoferrin (LTF) (Lactotransferrin (LTF))

Reactivité: Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Lactoferrin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 5F12-1-2

Détail du produit anti-Lactoferrin anticorps

Purification: Protein G purified

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Références pour anticorps anti-Lactoferrin (ABIN1107996)

Shimazaki, Kamio, Nam, Harakawa, Tanaka, Omata, Saito, Kumura, Mikawa, Igarashi, Suzuki: "Structural and immunochemical studies on bovine lactoferrin fragments." dans: Advances in experimental medicine and biology, Vol. 443, pp. 41-8, (1998) (PubMed).

Shimazaki, Nam, Harakawa, Tanaka, Omata, Saito, Kumura, Mikawa, Igarashi, Suzuki: "Monoclonal antibody against bovine Lactoferricin and its epitopic site." dans: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 58, Issue 12, pp. 1227-9, (1997) (PubMed).

Détails sur Lactoferrin

Antigène: Lactoferrin (LTF) (Lactotransferrin (LTF))

Autre désignation: Lactotransferrin

Sujet: Lactoferricin B is derived by enzymatic cleavage of lactoferrin which is a member of the transferrin family of metal-binding proteins found in milk and other secretory fluids and also in blood. Cleavage by pepsin of bovine lactoferrin leads to the release of Lactoferricin B (aminoacid 17-41). This peptide is highly basic, possessing five Arg (R) and three Lys (K) residues. In addition, a number of Trp (W) and Phe (F) aromatic residues are present. The two Cys (C) residues from lactoferricin B form a disulfide bond, generating an almost completely cyclical peptide. Nevertheless, the disulfide bond is not required for the antimicrobial potency. Several studies have shown that Lactoferricin B has a broad-spectrum activity against various Gram-positive and Gram-negative bacteria. In addition the peptide has been shown to have antifungal, antiviral and antitumour activity and to bind lipopolysaccharides (LPS, endotoxin). Moreover, it is known to stimulate the adaptive immune response and has anti-inflammatory properties. Lactoferricin B belongs to a large group of cationic antimicrobial peptides.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

ID gène: 9913

UniProt: P24627

Pathways: Transition Metal Ion Homeostasis